Venous Thromboembolism in DM1 (DM1-VTE)

Institut de Myologie, France

Status: Completed

Conditions: Pulmonary Embolism; Venous Thromboembolism; Myopathy; Myotonic Dystrophy 1; Deep Vein Thrombosis

Study type: Observational

Funder types: Other

Identifiers

NCT03141749

Institutmyologie

Details and patient eligibility

About

The risk for venous thromboembolism (VTE) in DM1 and in other inherited myopathies, which can lead to chronic immobilization, are unknown. The purpose of this study is to evaluate incidence of VTE in cohort of patients presenting with DM1 with a comparison to a group of other inheritable myopathies and to a community-based population.

Full description

A cohort of more that 2,800 adult patients admitted to our Institutions between January 2000 and November 2014 with genetically proven myopathy will be retrospectively included.

Any information relative to their demographic and genetic characteristics, their muscular functional status and the occurrence of VTE will be collected.

Statistical analysis will be performed to estimate the incidence of venous thromboembolism in this population, to identify predictors of VTE, and to compare its incidence to a community-based population.

Enrollment: 2,810 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years
• Genetically proven myopathy
• Admission in our institutions from January 2000 to November 2014

Exclusion criteria

• Patient refusal