Ventilation-perfusion (V/Q) Ratio and Alveolar Surface Area in Preterm Infants

King's College London

Status: Completed

Conditions: Bronchopulmonary Dysplasia

Treatments: Other: Calculation of ventilation-perfusion ratio

Study type: Interventional

Funder types: Other

Identifiers

NCT04936477

KCH20-138

Details and patient eligibility

About

To non-invasively estimate the alveolar surface area of the lungs of prematurely born infants by taking measurements of oxygen and carbon dioxide and utilizing functional morphometry.

Enrollment: 30 patients

Sex: All

Ages: 22 to 28 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

Exclusion criteria

• Congenital or chromosomal anomalies

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Assessment of alveolar surface area by functional morphometry

Experimental group

Description:

Non-invasive measurements of V/Q

Treatment:

Other: Calculation of ventilation-perfusion ratio