Ventilator-associated Pneumonia (VAP) and Humidification System

Hospital Sao Domingos

Status and phase: Unknown; Phase 4

Conditions: Ventilator-associated Pneumonia

Treatments: Device: HME filter Twin Star 55, Drager Medical, Germany; Device: Heated humidification

Study type: Interventional

Funder types: Other

Identifiers

NCT01546974

hsd2012

CEP026/2011 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to determine which humidification system is more effective in preventing pneumonia in mechanically ventilated patients. The study will compare a heat and moisture exchanger versus heated humidification.

Enrollment: 306 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients expected to require mechanical ventilation for at least 48 hours

Exclusion criteria

• Patients < 18 yo and pregnant

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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306 participants in 2 patient groups

HME filter

Experimental group

Treatment:

Device: HME filter Twin Star 55, Drager Medical, Germany

Heated humidificator MR 730 Fisher & Paykel

Experimental group

Treatment:

Device: Heated humidification