Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis (GUIMAUVE)

Poitiers University Hospital

Status: Completed

Conditions: Myasthenia Gravis; Guillain-Barre Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT07022028

GUIMAUVE study

Details and patient eligibility

About

Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols. To date, no study has compared weaning modalities from mechanical ventilation in patients with these two diseases. Our objective was to assess and compare for ventilator weaning modalities between patients mechanically ventilated for Guillain-Barré syndrome or for myasthenia gravis in a large-scale multicenter study.

Enrollment: 800 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: All patients mechanically ventilated for at least 48 hours for Guillain-Barré syndrome or myasthenia gravis -

Exclusion Criteria: Patients mechanically ventilated less than 48h or intubated for another reason than the neuromuscular disease.

Trial design

800 participants in 1 patient group

Patients mechanically ventilated for Guillain-Barré syndrome or for myasthenia gravis (two groups)