Ventricular Arrhythmias After Pulmonary Vein Isolation

Universitätsklinikum Hamburg-Eppendorf

Status: Completed

Conditions: Atrial Fibrillation; Ventricular Arrhythmias

Study type: Observational

Funder types: Other

Identifiers

NCT02699255

WF-01/16

Details and patient eligibility

About

The investigators study aimed to observe the occurrence of new premature ventricular complexes and other ventricular arrhythmias after pulmonary vein isolation.

Full description

Atrial fibrillation is the most common arrhythmia with a lifetime risk for development of over 20%. Pulmonary vein isolation is now established as therapy of choice for patients with symptomatic atrial fibrillation. It is well known that this interventional therapy inevitably modulates the intracardiac autonomic nervous system. While this ablation might alter atrial electrophysiology beneficially, the impact on ventricular electrophysiology remains unclear.

Enrollment: 111 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years
• Paroxysmal atrial fibrillation scheduled to undergo pulmonary vein isolation

Exclusion criteria

• Age < 18 years
• Persistent atrial fibrillation
• Life expectancy less than 12 months
• Acute myocardial infarction, coronary artery bypass graft surgery, open heart surgery, or percutaneous transluminal coronary angioplasty within less than 3 months prior to inclusion
• Documentation of >30 premature ventricular complexes per hour, salvos or ventricular tachycardias prior to atrial fibrillation ablation