Ventricular Remodeling In Patients With Aortic Stenosis Assessed Echocardiography

Lahey Health

Status: Withdrawn

Conditions: Aortic Stenosis

Study type: Observational

Funder types: Other

Identifiers

NCT00774657

2008-090

Details and patient eligibility

About

This preliminary study will compare the effectiveness of two-dimensional and three-dimensional echocardiographic measurements of wall thickness and left ventricular mass in patients with Aortic Stenosis

Full description

This study will evaluate left ventricular patterns of remodeling and hypertrophy in patients with aortic stenosis, and compare two-dimensional echocardiography measurements (wall thickness) with three-dimensional echocardiography data(left ventricular mass). Along with a second objective to assess Doppler diastolic filling indices associated with the various patterns of left ventricular remodeling.

Previous studies(see reference list) were primarily derived from two-dimensional echo data set(based on wall thickness). Various patterns of left ventricular remodeling have been described in response to increased pressure overload.

Three-dimensional echocardiography is a relatively new technique that is being increasingly used in the Echocardiography Lab in selected patients. This technique holds promise of being more accurate for volume-related measurements than the standard 2-dimensional echocardiography techniques.

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects more than 18 yrs of age through 90 yrs of age
• Both male and female
• Patients with moderate or severe isolated Aortic Stenosis
• Patients who have been referred for both two-dimensional and three- dimensional echocardiographies.

Exclusion criteria

• Poor acoustic windows
• h/o CAD and wall motion abnormality