Ventriculomegaly and Gait Disturbance in the Senior Population in the Region of Västerbotten (VESPR)

Umeå University

Status: Completed

Conditions: Gait Disorders, Neurologic; Central Nervous System Diseases; Idiopathic Normal Pressure Hydrocephalus (INPH); Dementia; Hydrocephalus, Normal Pressure; Brain Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT05204745

2017/335-31

Details and patient eligibility

About

Idiopathic normal pressure hydrocephalus (INPH) is a treatable disease of the elderly, typically causing gait impariment, dementia and urinary incontinence. The objective of this study is to make an epidemiological survey of INPH in Umeå, Sweden. Subjects with self-perceived gait impairments will be identified through a questionnaire. They will go through clinical examinations and have an MRI of the brain. A control population will also be investigated to enable comparisons between the populations. The main hypothesis is that the prevalence of INPH in the population is higher than what is previoulsy known.

Enrollment: 6,500 patients

Sex: All

Ages: 65 to 84 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Living in Umeå, Sweden.

Exclusion criteria

• Age <65 or >84 years when the questionnaire was sent out.
• Death at the time for the clinical evaluation.

Trial design

6,500 participants in 2 patient groups

Case

Description:

Subjects with subjective gait impariment according to questionnaire answers.

Control

Description:

Subjects without subjective gait impariment according to questionnaire answers.