Ventriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not? (VISION 2)

Duke University

Status: Terminated

Conditions: Subarachnoid Hemorrhage

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01169454

Pro00016054

Details and patient eligibility

About

The purpose of this study is to explore two currently accepted methods of intracranial pressure (ICP) management through cerebral spinal fluid (CRF) drainage for patients diagnosed with subarachnoid hemorrhage (SAH). This is a randomized observational study of two physician-prescribed approaches to managing ICP monitoring and CSF drainage for SAH patients. The study will enroll only those patients who have ICP monitoring. Because this is an observational study, there are no physical risks to the patient, the only risk is loss of confidentiality.

Full description

Patients diagnosed with subarachnoid hemorrhage (SAH) who require intracranial pressure (ICP) management through cerebral spinal fluid (CRF) drainage will be eligible for this study.

Subjects will be randomized to receive one of two currently accepted methods of ICP management. The first is ICP monitoring with intermittent CSF drainage and the second is through continuous CSF drainage at set pressure thresholds.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to Duke University NCCU
• Adult (18 years of age or older)
• Primary diagnosis is Subarachnoid Hemorrhage
• Intraventricular catheter in situ

Exclusion criteria

• Glasgow Coma Score = 3
• Hunt and Hess Score = 5
• Prisoners
• Ventriculostomy > 72 hours

Trial design

60 participants in 2 patient groups

Monitor then drain

Description:

Subjects who are treated with intermittent CSF drainage

Drain then monitor

Description:

Subjects who are treated with continuous CSF drainage at set pressure thresholds