Ventrointermediate Nucleus (VIM DBS) and Working Memory (WMVIM)

The Washington University

Status: Completed

Conditions: Essential Tremor

Study type: Observational

Funder types: Other

Identifiers

NCT00906412

06-0732

Details and patient eligibility

About

This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET) patients. We are especially trying to figure out how stimulation on each side of the brain may affect working memory.

Enrollment: 10 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

ET PATIENTS:

• Clinical diagnosis of essential tremor affecting the upper extremities.
• Previous unilateral or bilateral DBS of the VIM
• Ages 40 -70
• A useable pre-surgical MR scan

CONTROLS:

• Spouse or acquaintance of enrolled patient participant
• Ages 40 - 70

Exclusion criteria

ET PATIENTS:

• Clinical evidence of other neurological conditions
• Significant psychiatric condition

CONTROLS:

• Clinical evidence of other neurological conditions
• Significant psychiatric condition

Trial design

10 participants in 2 patient groups

ET Group

Description:

Total of 25 participants with ET

Controls

Description:

25 controls without ET