Verbal Suggestion to Reduce Pain and Anxiety During Unsedated Colonoscopy

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Status: Completed

Conditions: Patient Comfort; Colonoscopy; Anxiety; Pain; Sedation-Free Procedure

Treatments: Behavioral: Verbal Suggestion

Study type: Interventional

Funder types: Other

Identifiers

NCT07228884

2025-03/54

Details and patient eligibility

About

Colonoscopy is an important diagnostic and screening procedure for colorectal diseases, but it can cause pain and anxiety, especially when performed without sedation. Verbal suggestion techniques - in which the physician provides calm, positive, and encouraging communication during the procedure - may help reduce these unpleasant experiences.

This randomized controlled study aims to evaluate the effect of verbal suggestion on pain and anxiety levels of patients undergoing unsedated colonoscopy. Sixty adult patients will be randomly assigned to either a verbal suggestion group or a control group. In the verbal suggestion group, the endoscopist will use positive and supportive phrases during the procedure (for example: "You are doing great," "Take a deep breath, we'll get through this easily"). The control group will undergo colonoscopy without any verbal intervention.

Pain will be assessed using a Visual Analog Scale (VAS) and anxiety will be measured with the Beck Anxiety Inventory (BAI) before and after the procedure. Heart rate will also be monitored as an objective indicator of anxiety.

The goal of this study is to determine whether verbal suggestion can improve patient comfort and tolerance during colonoscopy without sedation, potentially providing a low-cost and practical method to enhance patient experience.

Enrollment: 102 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18 to 70 years.
• Patients scheduled for elective, diagnostic, or screening colonoscopy without sedation.
• Ability to understand and provide written informed consent.
• Ability to communicate verbally with the endoscopist during the procedure.
• ASA (American Society of Anesthesiologists) physical status classification I-II.

Exclusion criteria

• Refusal or inability to provide informed consent.
• Known psychiatric or neurological disorders that could affect anxiety or pain perception.
• Use of anxiolytic, sedative, or analgesic drugs within 24 hours before the procedure.
• Colonoscopy performed under sedation or anesthesia.
• Severe cardiopulmonary comorbidities (ASA class ≥ III).
• Incomplete colonoscopy due to technical or anatomical reasons.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

102 participants in 2 patient groups

Verbal Suggestion Group

Experimental group

Description:

Patients undergoing unsedated colonoscopy will receive positive verbal suggestion from the endoscopist throughout the procedure (e.g., "You are doing great," "Take a deep breath," "It will be over soon.")

Treatment:

Behavioral: Verbal Suggestion

Control Group

No Intervention group

Description:

Patients undergoing unsedated colonoscopy will receive standard communication without verbal suggestion during the procedure.