Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies (VANISH)

Natera

Status: Completed

Conditions: Trisomy 18; Trisomy 13; Trisomy 21; Vanishing Twin

Study type: Observational

Funder types: Industry

Identifiers

NCT05004337

21-050-NPT

Details and patient eligibility

About

The purpose of this study is to collect blood samples from women carrying a vanishing twin pregnancy to further develop Natera's non-invasive prenatal screening test to provide information about possible chromosomal conditions for the living twin

Enrollment: 126 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women with either ultrasound-documented dizygotic (DZ) twin pregnancy or those whose Panorama Test™ results suggest increased risk for vanishing twin

Exclusion criteria

• Monozygotic twin pregnancy
• Non twin pregnancy
• Maternal history of bone marrow or organ transplantation