Vertical Ridge Augmentation Using Computer-guided Sandwich Osteotomy Technique (RGD)

Al-Azhar University

Status and phase: Active, not recruiting; Phase 1

Conditions: Alveolar Bone Resorption

Treatments: Procedure: Sandwich technique with xenograft, collagen membrane and simultaneous implant placement.; Biological: Sandwich technique with (RGD), xenograft, collagen membrane and simultaneous implant placement.

Study type: Interventional

Funder types: Other

Identifiers

NCT07028606

Arginine - Glycine - Aspartic

Details and patient eligibility

About

Researcher will introduce the trial to patients and provide full explanation of its aim and benefits in Arabic language. Patients will then be able to have an informed discussion with the researcher. Researcher will obtain written consent from patients willing to participate in the trial

Full description

This protocol and the template informed consent form will be reviewed by the Ethics Committee of Scientific Research -Faculty of Oral and Dental Medicine- Al-Azhar University.

Enrollment: 12 estimated patients

Sex: All

Ages: 30 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

• Adults (age 30-45) with vertical ridge deficiency.
• Patients with maxillary vertical ridge deficiency 4-8mm according to Cologne Classification of Alveolar Ridge Defects (CCARD).
• Patients with good oral hygiene.
• Free from systemic diseases that may influence the outcome of the therapy.

Exclusion criteria

• Systemic conditions which are generally considered to be a contraindication to implant surgery which included but not limited to: osteoporosis, uncontrolled diabetes.
• Pregnant or lactating females
• Current or former smokers.
• Patient treated by immunosuppressive chemotherapy or radio therapy,
• Allergy to any material or medication used in the study.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: Single Blind

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12 participants in 2 patient groups, including a placebo group

Sandwich technique with xenograft, collagen membrane and simultaneous implant placement

Placebo Comparator group

Description:

(Control group) will receive computer-guided sandwich osteotomy technique with xenograft, collagen membrane and simultaneous implant placement.

Treatment:

Procedure: Sandwich technique with xenograft, collagen membrane and simultaneous implant placement.

Sandwich technique with (RGD), xenograft, collagen membrane and simultaneous implant placement

Active Comparator group

Description:

(Study group) will receive computer-guided sandwich osteotomy technique with (RGD), xenograft, collagen membrane and simultaneous implant placement.

Treatment:

Biological: Sandwich technique with (RGD), xenograft, collagen membrane and simultaneous implant placement.