Vertical Transmission of Hepatitis C in Adult Children of Female Baby Boomers

University of Pennsylvania

Status: Completed

Conditions: Hepatitis C, Chronic; Hepatitis C

Treatments: Diagnostic Test: HCV test; Other: Eligibility Screening

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03038763

826229

Details and patient eligibility

About

The investigators aim to determine the prevalence of hepatitis C in the adult children of female baby boomers. During the years baby boomers were becoming pregnant, hepatitis C testing was either not available or was not standard of care. Because of this, participants' children may be unaware of participants' risk of hepatitis C.

Enrollment: 100 patients

Sex: All

Ages: 18 to 72 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Mothers:

• Born between 1/1/45-12/31/64
• Black or white race
• Active or prior infection with hepatitis C
• Have at least one living adult child over the age of 18

Children:

• ≥18 years of age
• Born to mother with current or prior HCV infection, with likely timing of HCV acquisition prior to or during pregnancy
• Mother gave informed consent for child to be approached for study participation

Exclusion criteria

Mothers:

• Unwilling to disclose hepatitis C status to children

Trial design

100 participants in 2 patient groups

Mothers

Description:

Black or white mothers who have or have had hepatitis C and were born between 1945-1964. Participants must have at least one child over the age of 18.

Treatment:

Other: Eligibility Screening

Adult Children

Description:

Adult children of Black or white mothers who have or have had hepatitis C and were born between 1945-1964. From speaking with these mothers, it must be possible that participants were exposed to hepatitis C virus while in the womb.

Treatment:

Diagnostic Test: HCV test