Verticality Perception - Multisensory Contribution

University of Zurich (UZH)

Status

Completed

Conditions

Individual Contribution of Different Sensory Systems

Verticality Perception in Healthy Human Subjects

Treatments

Other: 3D-video-head impulse testing

Other: Vestibular-evoked myogenic potentials (VEMPs)

Other: Vestibular stimulation by use of the turntable (static roll-tilt while the head is roll-tilted relative to the trunk)

Study type

Interventional

Funder types

Other

Identifiers

NCT02212704

perception_head_roll_zurich

Details and patient eligibility

About

The purpose of this study is to evaluate the relative contribution of head- and trunk-based sensory systems to internal estimates of direction of gravity in healthy human subjects. To implement this assessment experimentally, the investigators will use a motor-driven 3D-turntable and a thermoplastic mask to keep the head in a stable, either roll-tilted (±30°) or aligned with the trunk. The investigators will then obtain measurements of the subjective visual vertical in seven different whole-body roll positions (max. 90° roll-tilt). Analysis will be driven by a state-of-the art Bayesian integration model. The investigators hypothesize that different sensory input signals are combined in a statistically optimal fashion.

Enrollment

12 patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

ages 18-60 years
informed consent
absence of exclusion criteria

Exclusion criteria

peripheral-vestibular deficit
disturbed consciousness
history of sensory deficits
visual field deficits
other neurological or systemic disorder which can cause dementia or cognitive dysfunction
intake of antidepressants, sedatives, or neuroleptics
pregnancy, unless excluded by a negative pregnancy test
known neck pain or status post neck trauma