Vestibular Function After Chemoradiotherapy for Nasopharyngeal Carcinoma

Clalit Health Services

Status: Unknown

Conditions: Nasopharyngeal Carcinoma

Treatments: Radiation: Chemoradiotherapy for nasopharyngeal carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT02505672

0361-14-RMC

Details and patient eligibility

About

Nasopharyngeal carcinoma (NPC) is usually treated with chemoradiotherapy. While the effects of this treatment on cochlear function is well characterized, its effect on vestibular function is not well studied.

In this study the investigators will study the vestibular function of 50 patients undergoing chemoradiotherapy for NPC both before and after treatment in order to better define its effects. All patients will undergo a validated questionnaire (dizziness handicap index), posturography, audiometry and vestibular-evoked myogenic potentials.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 years or older.
• Biopsy-proven NPC.
• About to undergo chemoradiotherapy with intensity-modulated radiotherapy (IMRT).

Exclusion criteria

• Pregnancy.
• Prior vestibular dysfunction.

Trial design

50 participants in 1 patient group

Study group

Description:

Patients older than 18 who are planned to undergo chemoradiotherapy for nasopharyngeal carcinoma.

Treatment:

Radiation: Chemoradiotherapy for nasopharyngeal carcinoma