Vestibular Pain Interactions (VPI)

University of Zurich (UZH)

Status: Completed

Conditions: Healthy

Treatments: Procedure: Vection stimulation; Procedure: CHEPS; Procedure: Quantitative sensory testing; Procedure: 3D Turntable

Study type: Interventional

Funder types: Other

Identifiers

NCT02358954

VPI01

Details and patient eligibility

About

The goal is to establish the practical usefulness of vestibular stimulation for modulating pain perception and to describe the possible mechanisms that could underlie neural vestibular-somatosensory interactions.

Enrollment: 26 patients

Sex: Male

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Weight: 50 - 100 kg
• Height: 155 - 185 cm
• Male subjects 18 years to 60 years of age
• Sufficient command of German language
• Written informed consent by the participant after information about the project
• Without any known history of neurological disease (especially motor, somatosensory disorders, peripheral neuropathies).
• Right-handedness

Exclusion criteria

1. Intellectually or mental impaired subjects
2. Drug abuse
3. Chronic alcohol consumption
4. No use of marihuana 24h before measurements.
5. No history of vestibular or auditory disorders.
6. Diabetes mellitus
7. Participants of other studies during study period and 30 days prior to study begin
8. Any regular concomitant medication
9. Abnormal QST parameters at the baseline measurement.
10. Absent CHEPs-Potentials at the baseline measurement.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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26 participants in 1 patient group

Vestibular Pain interactions

Experimental group

Treatment:

Procedure: 3D Turntable

Procedure: CHEPS

Procedure: Quantitative sensory testing

Procedure: Vection stimulation