Vestibulopathy With Vestibulo Ocular Reflex (VOR) Gain Deficit

University of Haifa

Status: Unknown

Conditions: Vestibulopathy, Acute Peripheral

Treatments: Other: physical therapy program (group); Other: physical therapy program (computerized exercises)

Study type: Interventional

Funder types: Other

Identifiers

NCT03271775

UHaifa2808

Details and patient eligibility

About

The study is examine the eye movements characteristics of patients with VOR gain deficits (overt and covert saccades) before and after physical therapy intervention program and examine the most effective physical therapy treatment program for patients with vestibulopathy.

Full description

The vestibular system receives and conveys information about head motion in space, and is the main human sensory system dedicated to detecting self-motion.The vestibular system plays a crucial role in static and dynamic balance control, stabilizing the head and trunk, especially on unstable surfaces . In terms of postural control and falls, the literature describes a direct association between VOR deficits, gait instability, and falls.The "gain" of the VOR is defined as the change in the eye angle divided by the change in the head angle during the head turn. Under ideal conditions, the gain of the rotational VOR is 1.0, meaning there is a compensatory eye velocity equal to the head velocity and in the opposite direction. In case of a positive vHIT, the VOR gain is decreased and refixating saccades are observed. The video Head Impulse Test measures eye velocity during head rotation. Instant feedback about every single head impulse allows the examiner to apply a set of standardized graded impulses. The system is easy to use in a clinical setting, provides an objective measure of the VOR, and detects both overt and covert catch-up saccades in patients with vestibular loss. Measurements are quick and noninvasive, and the automated analysis software provides instant results.

Enrollment: 100 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with unilateral or bilateral vestibulopathy living independently in the community

Exclusion criteria

• cognitive state decline neurological disorder disease or disorders that can affect balance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 3 patient groups

control group

No Intervention group

Description:

Patients in the control group will follow the doctor's instructions (medications and etc.) and will not participate in any physical therapy program.

PT treatment group for balance disorder

Experimental group

Description:

Patients in this research group will join to a 3 months' physical therapy treatment group designed to improve balance. The service for the group is provided by laboratory.

Treatment:

Other: physical therapy program (group)

independant home computerized exercises

Experimental group

Description:

Patients in this group will be treated by 3 months' independent home computerized exercise program. Each patient will receive a personal access code for the exercise program. The duration of each practice is 5-10 minutes per day.

Treatment:

Other: physical therapy program (computerized exercises)