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Vibration Induced Reflex Responses and Estimation of TVR (VIRR&TVR)

I

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Status

Completed

Conditions

Muscle
Physiology

Treatments

Device: vibrator

Study type

Interventional

Funder types

Other

Identifiers

NCT03424551
IstPMRTRH-BMR1

Details and patient eligibility

About

The aim of this study is to estimate tonic vibration latency and whole body vibration reflex latency

Full description

This study was included 17 patients with spastic spinal cord lesions and 23 healthy control.

Soleus T-reflex, soleus H-reflex, soleus tonic vibration reflex (TVR), and reflex muscle response induced by whole body vibration was evaluated this study. To obtain the H-reflex response, the tibial nerve in the popliteal region was stimulated by using a stimulator (FE155 Stimulator HC ADInstrument, Oxford UK) with 1 ms-pulse current. The records was taken with the Ag / AgCl electrodes (Kendall ®Coviden, self-adhesive electrodes) placed on skin according to the SENIAM protocol. To obtain T-reflex response, an electronic reflex hammer (Elcon 100-150 Germany) was used. After H-reflex and T reflex records at rest, to obtain Tonic vibration reflex, local vibration was applied to the Achilles tendon at 50, 85, 140, 185, 235 and 265 Hz. To obtain the reflex response induced by Whole body vibration, vibration was applied at 35, 37, 39, 41, 43 and 45 Hz. Tibial nerve stimulation was performed again to determine Hmax during whole body vibration and local vibration.H-reflex records was taken while the subject is sitting on a chair.

The data was recorded with the PowerLab data acquisition device (ADInstrument Oxford UK). For Whole-body vibration, PowerPlate Pro5 (London UK) was used.

Enrollment

40 patients

Sex

All

Ages

20 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria spinal cord injury patients:

  • Spastic spinal cord lesion
  • Patients between the ages of 20 and 45

Exclusion Criteria for spinal cord injury patients

  • Accompanying trauma

    1. Lower extremity fracture
    2. Lower extremity peripheral nerve lesions
    3. Head trauma
  • Autonomic dysreflexia

  • Heterotopic ossification

  • Lesions in calf skin

  • Excessive spasticity (Ashwort4) / Contracture (knee, hip, footbath)

  • Peripheral nerve-vascular diseases / muscle diseases

  • Pressure ulcer (> Grade 2)

Inclusion criteria for Control

  • Ages 20 and 45 old years
  • Both sex
  • Healthy volunteers

Exclusion Criteria for Control

  • Pregnant women

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

40 participants in 1 patient group

Vibrator
Experimental group
Description:
Local or Whole body vibration was applied at six different frequencies to Healthy control and spastic spinal cord injury. For local vibration, vibration frequencies were 50, 85, 140, 185, 235 and 265 Hz . For whole body vibration, vibration frequencies were 35, 37, 39, 41, 43 and 45 Hz
Treatment:
Device: vibrator

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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