ClinicalTrials.Veeva

Menu

Video Capsule Endoscopy for Detection of Gastrointestinal Bleeding in the Small Bowel

U

University Hospital Freiburg

Status

Enrolling

Conditions

GastroIntestinal Bleeding

Treatments

Device: Small bowel capsule endoscopy

Study type

Observational

Funder types

Other

Identifiers

NCT05949268
Capsule endoscopy_FR

Details and patient eligibility

About

Small bowel capsule endoscopy is the main diagnostic standard for small bowel bleeding. This study investigates the detection rate of small bowel bleeding in capsule endoscopy and further endoscopic treatment in a prospective and retrospective cohort.

Full description

Small bowel capsule endoscopy is considered the diagnostic gold standard in the diagnosis of diseases of the small bowel. Most indications for capsule endoscopy are overt small bowel bleedings - defined as gastrointestinal bleeding after negative gastroscopy and colonoscopy - or occult iron deficiency anemia. Timing of small bowel capsule endoscopy seems to be decisive for the diagnosis of small bowel bleeding: corresponding to the actual guidelines the detection of small bowel bleeding can be up to > 70% if the intervention is performed within 2 days. Treatment of small bowel bleedings can be performed with small bowel enteroscopy such as balloon or motorized spiral enteroscopy. Against this background this study investigates the rate of small bowel bleeding diagnosed in capsule endoscopy. The aim of the study is to report tumorous, vascular and inflammatory findings as well as complications and cecal accessibility. One focus of the study is the time between small bowel bleeding and small bowel capsule endoscopy and small bowel enteroscopy, respectively. Endoscopic therapies and further bleeding episodes are recorded. In order to determine the improved clinical outcome after the introduction of the shortened timing for recommendation published in 2022, a retrospective cohort should be included in addition to a prospective cohort.

Enrollment

1,300 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • suspicion of gastrointestinal bleeding in the small bowel undetected by gastroscopy and colonoscopy
  • informed consent

Exclusion criteria

  • contraindications for small bowel capsule endoscopy (e.g. stenosis)

Trial design

1,300 participants in 1 patient group

Patients with gastrointestinal bleeding undetected in gastroscopy and colonoscopy
Description:
Gastrointestinal bleeding in the small bowel.
Treatment:
Device: Small bowel capsule endoscopy

Trial contacts and locations

1

Loading...

Central trial contact

Dominik Bettinger, MD; Michael Schultheiss, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems