Video Education and Behaviour Contract to Optimize Adherence in Renal Transplants (VECTOR)

University of Saskatchewan

Status: Completed

Conditions: Medication Adherence; Kidney Transplantation

Treatments: Behavioral: Video education + adherence contract

Study type: Interventional

Funder types: Other

Identifiers

NCT03540121

99399

Details and patient eligibility

About

This study aims to test the effectiveness of an electronic-based video intervention and behavioral contract on improving medication adherence among kidney transplant recipients.

Full description

Non-adherence to immunosuppressive medications is a major problem after kidney transplantation, leading to increased rejections, hospitalizations and health care expenditures. Effective educational opportunities may positively influence adherence, especially when combined with a behavior intervention. However, increasing education and support to transplant recipients demands greater use of care providers' time and resources in a health care system that is already stretched.

A patient-oriented video series has been developed according to best practices for transplant education, featuring an animated character embarking on a transplant journey. Animated segments illustrate difficult concepts for patients with poor health literacy, and patient narratives provide support and encouragement. A multicenter randomized controlled trial will be conducted with 4 sites across North America. Patients will be randomized (1:1) to either the intervention (i.e., home-based video education + adherence contract plus usual care) or usual care alone. Patients will be enrolled in the study prior to hospital discharge and will be provided with access to the video intervention and contract electronically. The primary outcome will be adherence at 12 months post-transplant, as measured by self-report (BAASIS), and variability in immunosuppressant levels. Secondary outcomes include the change in knowledge score between the intervention and control in groups (measured by the Kidney Transplant Understanding Tool); differences in self-efficacy (Generalized Self-efficacy Scale), beliefs about medicines (Beliefs of Medicine Questionnaire), and quality of life (SF-12). Individualized viewing statistics will be analyzed to determine patient uptake, and satisfaction about the educational experience will be captured on a self-reported survey.

Enrollment: 173 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 or older
• can speak and understand and read English
• receive their first kidney transplant at one of the participating sites during enrolment

Exclusion criteria

• do not meet inclusion criteria
• have previously participated in a study entitle "Improving health outcomes of kidney recipients: A randomized controlled trial of a pre-transplant education intervention"

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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173 participants in 2 patient groups

Video education + adherence contract

Experimental group

Description:

electronically delivered video education (at transplant discharge) + electronic adherence contract (1 month after enrolment)

Treatment:

Behavioral: Video education + adherence contract

Standard education

No Intervention group

Description:

standard of care education provided at each transplant center (control emails will be provided at intervention time points)