Video Screening for Visual Impairment of Infants

Sun Yat-sen University

Status: Completed

Conditions: Behavioral Dynamics; Visual Impairment

Treatments: Behavioral: Video recording for behaviors

Study type: Observational

Funder types: Other

Identifiers

NCT04237350

CCPMOH2019-China-7

Details and patient eligibility

About

An individual senses the world and reflects feedbacks via independent behaviors. Such precise collaboration of the sensory and behavioral systems is fundamental to survival and evolution. When a sensory modality is altered, the behavioral system has the potential to fit in a substitute modality. However, the specific dynamics of human behaviors in response to sensory loss remain largely unknown due to the paucities of representative situations and large-scale samples.

Here, the investigators focused on thousands of human infants who suffered varying degrees of visual stimuli deficiency in early stages, while their behavioral systems remained sensitive and thus retained high behavioral plasticity. Having access to this unique population provides an unprecedented opportunity to investigate the effect of diverse visual conditions on the behavioral system and develop a domestic apparatus for screening visual impariment of infants.

Enrollment: 3,652 patients

Sex: All

Ages: Under 4 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Younger than 4 years of age

Exclusion criteria

• Any brain and mental illnesses, or other known illnesses that may affect the behavioral patterns

Trial design

3,652 participants in 3 patient groups

severe visual impairment group

Description:

The "severe visual impairment" group is defined as the BCVA of at least one eye outside the 99% referenced range or worse than light perception with structural abnormalities or other examination results.

Treatment:

Behavioral: Video recording for behaviors

likely healthy group

Description:

For the "likely healthy" group, the visual acuity of both eyes is in the 95% referenced range with no structural abnormalities. The referenced range could be found in the following publication: Mayer, DL., et al. Monocular acuity norms for the Teller Acuity Cards between ages one month and four years. Investigative Ophthalmology \& Visual Science. 36(3):671 (1995)

Treatment:

Behavioral: Video recording for behaviors

mild visual impairment group

Description:

The "mild visual impairment" group is defined as the BCVA in the 99% referenced range in both eyes with abnormalities of structure or other examination results.

Treatment:

Behavioral: Video recording for behaviors