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VIdeo Telehealth in ALzheimer's: NeuroPsychology (VITAL-NP)

University of Colorado Denver (CU Denver) logo

University of Colorado Denver (CU Denver)

Status

Completed

Conditions

Suspected Typical Alzheimer's Disease (AD)
Suspected Atypical Alzheimer's Disease (AD)

Treatments

Behavioral: Face-to-face evaluation (FF)
Behavioral: TeleNP evaluation

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT05379023
R21AG072153 (U.S. NIH Grant/Contract)
21-5037

Details and patient eligibility

About

The overarching goal of this study is to a) assess the feasibility and preliminary validity of home-based delivery of TeleNP to patients with suspected Alzheimer's Disease (AD), referred for cognitive assessments in a Neurology Clinic; and b) elucidate whether TeleNP is equivalent to face-to-face evaluation (FF) for diagnostic adjudication of atypical versus typical AD.

Enrollment

66 patients

Sex

All

Ages

60 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Individuals age 60 to 90 years who are undergoing evaluation for possible AD and whose severity ranges from MCI to mild dementia.
  • Individuals must carry a diagnosis of either suspected typical AD or atypical AD, based on the referring neurologist's diagnosis.

Exclusion criteria

  • Individuals with moderate to severe levels of dementia and individuals with active delirium (per neurologist's determination).
  • Individuals who are legally blind or deaf, due to the auditory and visual components of the study.
  • Individuals with a brain tumor and individuals who have a confirmed nonAD neurological diagnosis (e.g, Multiple Sclerosis; FTD).
  • Individuals who are being evaluated outside of the UCH Memory Disorders Clinic.
  • Individuals who report active (i.e., within the last 6 months) substance use of illicit drugs such as cocaine or methamphetamines, or who carry a diagnosis of a major psychiatric disorder (e.g., schizophrenia; bipolar disorder).

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

66 participants in 2 patient groups

Face-to-face evaluation (FF), TeleNP evaluation
Other group
Treatment:
Behavioral: TeleNP evaluation
Behavioral: Face-to-face evaluation (FF)
TeleNP evaluation, Face-to-face evaluation (FF)
Other group
Treatment:
Behavioral: TeleNP evaluation
Behavioral: Face-to-face evaluation (FF)

Trial contacts and locations

1

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Central trial contact

Neurology Research Partners; Jennifer Krupa, BA

Data sourced from clinicaltrials.gov

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