Videoendoscopic Drainage of Infected Pancreatic Collections

National Institutes of Health (NIH)

Status: Completed

Conditions: Pancreatitis, Acute Necrotizing

Treatments: Procedure: Videoscopic-Assisted Retroperitoneal Debridement (VARD)

Study type: Interventional

Funder types: NIH

Identifiers

NCT00061269

VDIPC (completed)

R03DK061362 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The VARD (Videoendoscopic Assisted Retroperitoneal Drainage) approach as treatment for necrotizing pancreatitis proposes an alternative to standard complicated open abdomen treatment methods.

This treatment involves making a small incision and looking inside the abdomen with a videoendoscope. A videoendoscope is an instrument with a small camera and light on the end. It also has an extension tool that the surgeon can use to clean out any dead and infected tissue in the abdomen.

This approach may reveal a treatment opportunity with faster recovery potential and shorter hospitalizations for patients with necrotizing pancreatitis.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Pancreatic necrosis or peripancreatic fluid collection following acute pancreatitis noted on CT scan
• Infected pancreatic necrosis or pancreatic abscess and determined by + FNA (gram stain or culture), as defined by the Atlanta Symposium
• Not neutropenic or pregnant
• No prior necrosectomy
• No pancreatic pseudocyst, either sterile or infected

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

VARD

Experimental group

Description:

Videoscopic-Assisted Retroperitoneal Debridement (VARD)

Treatment:

Procedure: Videoscopic-Assisted Retroperitoneal Debridement (VARD)