Virtual Environments in Patients Receiving Treatment for Cancer (VE)

Cyprus University of Technology

Status: Completed

Conditions: Mood Disturbances

Treatments: Behavioral: Guided Imagery; Behavioral: Immersive Virtual Reality (VR)

Study type: Interventional

Funder types: Other

Identifiers

NCT02392728

AC-VES-91

Details and patient eligibility

About

The mood disturbances that lung cancer patients experience during and after chemotherapy have a debilitating effect on their quality of life. The goal of the proposed project is to develop and test an intervention that relies on the use of immersive Virtual Reality (VR) to combat the adverse psychological/emotional consequences of receiving treatment for cancer. Although VR has been used with success to treat various psychological conditions (e.g., phobias, PTSD), its potential in helping cancer patients experience an improved mood and hence better quality of life has not yet been tested. In this project the investigators will first develop the virtual content (e.g., natural scenes) that patients will experience within a Head-Mounted-Display, simulating movement by manipulating a gesture controller. The investigators will then carry out a randomized, double blind, crossover trial with 50 hospitalized cancer patients to test whether they can benefit psychologically and emotionally from their interaction with an immersive environment compared to those who will experience a guided imagery intervention. A positive result will open the route for the future development of affordable self-administered VR solutions for treating the psychological side-effects of cancer treatment.

Full description

Although VR has been used with success to treat various psychological conditions (e.g., phobias, PTSD), its potential in helping cancer patients experience an improved mood and hence better quality of life has not yet been tested. In this project the investigators will first develop the virtual content (e.g., natural scenes) that patients will experience within a Head-Mounted-Display, simulating movement by manipulating a gesture controller. The investigators will then carry out a randomized, double blind, crossover trial with 50 hospitalized cancer patients to test whether they can benefit psychologically and emotionally from their interaction with an immersive environment compared to those who will experience a guided imagery intervention. A positive result will open the route for the future development of affordable self-administered VR solutions for treating the psychological side-effects of cancer treatment.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients will be included if they had a histopathological diagnosis of cancer (different types are allowed)
• were 18 years or older, on active treatment and were receiving care at the hospital as inpatients
• Eligible participants will need to be able to speak and understand Greek and they had given written informed consent
• Participants should also have a score of >60 on the POMS total mood disturbance scale, a >50 on the Karnofsky Performance Scale Index
• a mean of >50 on the Attentional Function Index (AFI)

Exclusion criteria

• Patients were excluded if they were receiving palliative care
• they had an impaired cognitive ability or
• they had an impaired visual ability

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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50 participants in 2 patient groups

Intervention VE

Experimental group

Description:

Session of Immersive Virtual Reality (VR) and Session of Guided Imagery

Treatment:

Behavioral: Guided Imagery

Behavioral: Immersive Virtual Reality (VR)

Intervention GI

Active Comparator group

Description:

Session of Immersive Virtual Reality (VR) and Session of Guided Imagery

Treatment:

Behavioral: Guided Imagery

Behavioral: Immersive Virtual Reality (VR)