Virtual Histology Intravascular Ultrasound to Evaluate Prognostic Risks of Saphenous Vein Graft Disease Before Percutaneous Coronary Intervention.

Tianjin Chest Hospital

Status: Unknown

Conditions: Percutaneous Coronary Intervention; Major Adverse Cardiovascular Events; Virtual Histology Intravascular Ultrasound; Saphenous Vein Graft Disease

Treatments: Diagnostic Test: virtual histology intravascular ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT03175952

16YFZCSY00800

Details and patient eligibility

About

The study is a prospective cohort study conducted in Tianjin Chest Hospital, China. Patients with saphenous vein graft disease after coronary artery bypass graft, and planning for receiving percutaneous coronary intervention after virtual histology intravascular ultrasound will be enrolled between May 2017 and April 2019. These subjects will be followed up at 1, 6 and 12 months post-operation of PCI to assess the short-term and long-term effect.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with SVGD after CABG
• Planning to receive PCI using drug-eluting stents
• 18 to 80 years old
• Finishing VH-IVUS examination
• Willing to participate in the study and sign informed consent

Exclusion criteria

• Patients with liver disfunction and renal failure
• Aspirin and clopidogrel allergy
• Acute myocardial infarction after CABG
• History of stroke in the past 3 months
• Gastrointestinal bleeding and hemoptysis recently
• Vasculitis and non-atherosclerotic coronary artery disease
• Coagulation disorders
• History of malignancy
• Women during pregnancy

Trial design

120 participants in 1 patient group

PCI

Treatment:

Diagnostic Test: virtual histology intravascular ultrasound