Virtual Kidney Check and Follow-up

University of Manitoba

Status: Begins enrollment in 1 month

Conditions: Kidney Disease, Chronic

Treatments: Other: population-based screening for chronic kidney disease

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT06223750

HS24845 (H2021:170)

Details and patient eligibility

About

The goal of this clinical trial is to determine the most effective way to complete population-based screening for chronic kidney disease (CKD) in First Nations adults in Manitoba. The main questions it aims to answer are:

• To identify chronic kidney disease in First Nations adults in Manitoba
• To risk stratify patients as low, moderate and high risk of kidney failure and organize active surveillance by risk category
• To initiate treatments to prevent to progression of chronic kidney disease in individuals at risk of kidney failure

Participants will be randomized to:

1. Patient contact via mail with a letter and laboratory requisition for serum creatinine and urine Albumin Creatinine Ratio
2. Patient and primary care network contact via mail with a letter but no laboratory requisition

The primary outcome is the difference between groups in the proportion of individuals who undergo screening for chronic kidney disease within 6 months.

Enrollment: 3,356 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>= 18 years
• Resident of Manitoba
• First Nations
• Urban, rural or remote location

Exclusion criteria

• Kidney failure (dialysis or transplant)
• chronic kidney disease (estimated Glomerular Filtration Rate <60 milliliter/1.73square meter for 3 months)
• Screening for chronic kidney disease with estimated Glomerular Filtration Rate or Albumin to Creatinine ratio in the last 2 years

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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3,356 participants in 2 patient groups

Patient contact via mail with a letter and laboratory requisition

Other group

Description:

Patient contact via mail with a letter and laboratory requisition for serum creatinine and urine albumin to creatinine ratio

Treatment:

Other: population-based screening for chronic kidney disease

Patient and primary care network contact via mail with a letter but no laboratory requisition

Other group

Treatment:

Other: population-based screening for chronic kidney disease