Virtual Reality-based Interactive Treadmill Gait Training System for Parkinson's Disease

Seoul National University

Status: Completed

Conditions: Virtual Reality; Rehabilitation; Parkinson's Disease

Treatments: Device: Virtual reality-based interactive treadmill training; Device: Treadmill training without VR-based interaction

Study type: Interventional

Funder types: Other

Identifiers

NCT03686462

B-1806/474-002

Details and patient eligibility

About

Virtual-reality-based interactive treadmill system will be applied to the Parkinsons' disease patients who can walk (Hoehn and Yahr stage 2 to 4). Subjects will be randomly allocated to either VR-based treadmill training group or treadmill training without VR-based interaction. The training will be provided for 3 sessions (30min/session)/week for 4weeks, the total of 12 sessions. The outcomes will be measured at baseline, immediately after the completion of the intervention and 1 month after the intervention.

Enrollment: 22 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• definite or probable idiopathic Parkinson disease patient
• age from 18 to 80 years old
• H&Y stage 2 to 4 and who can walk 10 meter independently regardless of the use of gait aids

Exclusion criteria

• unstable medical conditions
• cognitive impairments which interfere with participation in virtual-reality based training
• hemispatial neglect, visual disturbance, apraxia
• other pre-existing disease involving the central nervous system (e.g. stroke, brain tumor)
• requiring the continuous manual assist with touch during the treadmill training
• can not give a consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

22 participants in 2 patient groups

Virtual reality-based interactive treadmill training

Experimental group

Description:

In this group, the subjects will receive virtual reality (VR)-based interactive treadmill training. During the 30-min training session, VR based interaction and feedback will be provided; the foot location will be visualized in the VR screen (semi-immersive condition), the obstacles will be seen in the screen from which subjects has to avoid, gait speed will be visualized, slopes of the treadmill will be changed according to the slope changes in VR and distractors will be added. Dual tasks will also be provided. Subjects in this group will receive a 30min/session, 3 sessions/week for 4 weeks, the total of 12 sessions of VR-based training.

Treatment:

Device: Virtual reality-based interactive treadmill training

Treadmill training without VR-based interaction

Sham Comparator group

Description:

The subjects in this group will receive the treadmill gait training. Virtual reality environment will be provided during the gait training but no feedback and interaction will be provided. Subjects in this group will receive a 30min/session, 3 sessions/week for 4 weeks, the total of 12 sessions of treadmill-based training.

Treatment:

Device: Treadmill training without VR-based interaction