Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment

Gulhane School of Medicine

Status and phase: Completed; Phase 4

Conditions: Hypogonadism

Treatments: Drug: Testosterone

Study type: Interventional

Funder types: Other

Identifiers

NCT02111434

GSM-022014

Details and patient eligibility

About

The study is designed to answer the following questions:

1. What is the levels of visceral adiposity index and Triglycerides/HDL cholesterol ratio in hypogonadism?
2. What is the effect of testosterone replacement on the visceral adiposity index and Triglycerides/HDL cholesterol ratio?

Full description

This is a retrospective design, which is performed by investigating the registrations of patients with hypogonadotrophic hypogonadism between the years 2007-2010.

Enrollment: 150 patients

Sex: Male

Ages: 18 to 26 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men
• Congenital hypogonadism
• Treatment Naive

Exclusion criteria

• Previous history of androgen replacement
• Hypertension
• Diabetes mellitus

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

150 participants in 1 patient group

testosterone

Experimental group

Description:

testosterone gel per day for 6 months testosterone 250 mg injection per 3-4 weeks for 6 months

Treatment:

Drug: Testosterone