Visual Field Defect Estimation Using Sequentially Optimized Reconstruction Strategy on Healthy and Glaucoma Subjects

Insel Gruppe AG, University Hospital Bern

Status

Completed

Conditions

Glaucoma, Open-Angle

Treatments

Diagnostic Test: Visual field testing

Study type

Observational

Funder types

Other

Identifiers

NCT03325751

2017-01540

Details and patient eligibility

About

Perimetry is a well-established method that is used to measure the visual field functions of humans. Commercially available products, such as the OCTOPUS 900 (Haag-Streit AG, Koeniz, Switzerland), are commonly used for assessing the visual field. Such devices are of critical value for patients suffering of glaucoma and neuro-ophthalmic conditions. The operating principle is to sequentially present light stimuli of different intensity at different locations within the visual field in an automatic way. Algorithms that select what locations and intensities to present over time are called strategies. These have the goal to provide both a fast and accurate estimation of the visual field function.

Recently, new strategies were developed that are faster and equally accurate as the strategies used today. The technological advancement of these new methods lies primarily in the ability to estimate location sensitivities without observing them directly but by leveraging previously queried locations. For this the investigators plan to implement the next generation of perimetry strategies into an OCTOPUS 900 and to test it in healthy subjects and glaucoma patients.

Enrollment

103 patients

Sex

All

Ages

40 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Cataract yes or no
Age range 40 - 80 years
Normal visual field (MD: < +2 dB)
Refractive error within ±5 dpt. spherical equivalent
Astigmatism of < -3 dpt.
Visual acuity of ≥0.3 logMar (decimal ≥0.5)
Experience in perimetry (history of at least one perimetry examination)
False positive or negative errors each less than 20% in each examination
Primary open-angle/ pseudoexfoliation/ primary angle-closure glaucoma
Early to moderate visual field loss (MD: +2 to +12 dB)
Written informed consent

Exclusion criteria

Exclusion criteria are children (<18 years old), inability to follow the procedure, insufficient knowledge of project language, the history of other ocular diseases than glaucoma or cataract or other conditions that might affect visual field testing (e.g. pituitary lesions, demyelinating diseases).