Visual Mode Switching in Color Perception

University of Minnesota (UMN)

Status: Withdrawn

Conditions: Perception of Things Changing Color; Adaptive Behavior

Treatments: Behavioral: Mode Switching Training

Study type: Interventional

Funder types: Other

Identifiers

NCT05779228

STUDY00002354

Details and patient eligibility

About

Participants will be given experience wearing colored lenses that add a tint to the environment. Changes in visual perception and neural processing that arise as a result of this experience will be measured. These are expected as participants learn to switch to "colored lenses mode" where the effects of the lenses are discounted and colors appear more normal as soon as the lenses are put on.

Full description

All participants will wear tinted lenses for 1 hour at a time, 5 times per day. Perception (behavior) and neural function (with functional MRI and EEG) before and after this experience will be measured. In the neural measurements, activity will be recorded while participants view stripes of many different colors both with the lenses on and off. In the perceptual measurements, participants will adjust the color of a small patch to appear neutral, neither red nor green. Behavior will be measured in a variety of conditions to test different hypotheses about the origins of the mode-switching effects. These include: 1) surrounding the patch with different colors, 2) preceding the presentation of the patch with presentation of different colors, 3) presenting the tests in a red-illuminated room, 4) presenting the tests in a completely darkened room, and 5) using a head-mount-display (virtual reality goggles) to present simulated lenses that gradually change in strength.

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal or corrected to normal vision by contact lenses
• No known visual disorders
• Little to no experience in tinted environments (e.g. dark rooms, swimming goggles)

Exclusion criteria

• Abnormal color vision

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 6 patient groups

Color Contrast

Experimental group

Description:

Test patch is surrounded spatially by different colors

Treatment:

Behavioral: Mode Switching Training

Color Adaptation

Experimental group

Description:

Test patch is surrounded temporally (preceded) by different colors

Treatment:

Behavioral: Mode Switching Training

Neuroimaging

Experimental group

Description:

Functional MRI and Electroencephelography data are acquired for multiple test colors

Treatment:

Behavioral: Mode Switching Training

Red Room

Experimental group

Description:

Participants are tested in a red-illuminated room

Treatment:

Behavioral: Mode Switching Training

Dark Room

Experimental group

Description:

Participants are tested in a completely darkened room

Treatment:

Behavioral: Mode Switching Training

Gradual Change

Experimental group

Description:

Participants view a gradual change in tint, presented on a head-mounted display

Treatment:

Behavioral: Mode Switching Training