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Visual Performance With Spatial Light Modulator

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University of Houston

Status

Unknown

Conditions

Normal Healthy Eyes

Treatments

Device: Spatial light modulator

Study type

Interventional

Funder types

Other

Identifiers

NCT05134896
STUDY00003209

Details and patient eligibility

About

Eye's aberrations have been known to degrade human visual performance and the visual performance is significantly improved when correcting the aberrations in the central visual field. However, how the aberration correction affects the peripheral visual performance is not well understood. Moreover, how central and peripheral vision interacts remains unclear.

To conduct the study, we will use an adaptive optics vision simulator equipped with a Shack-Hartmann wavefront sensor and a spatial light modulator (see details in procedures section of the protocol). This system is capable of noninvasively controlling the eye's optical quality and evaluating visual performance simultaneously over a wide area of visual space. This study provides insights into the visual performance in the periphery visual field, and interaction between central and peripheral visual fields.

The goal of this study is to evaluate the visual performance at central and peripheral visual fields after correcting the ocular aberrations. An optical system equipped with a liquid crystal spatial light modulator will be used to achieve this goal non-invasively.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

A person is eligible for inclusion in the study if he/she:

  • Is between the ages of 18 and 60.
  • Has normal corneas i.e. no corneal infections, no systemic pink eye, no clinically significant dry eye, and no corneal dystrophies.
  • Has refractive errors less than +/- 10.0 Diopters in both eyes.

Exclusion criteria

A person will be excluded from the study if he/she:

  • Adults between the ages of 18-60 who are unable to give informed consent
  • Individuals below 18 years old
  • Individuals above the age of 60
  • Pregnant women (self-reporting, hormonal changes may alter the refractive status of the eye)
  • Prisoners
  • Students for whom you have direct access to/influence on grades
  • People who do not understand or speak English
  • Has clinically significant dry eye.
  • Has clinically significant cataract.
  • Has spherical refractive error that exceeds the limits outlined above.
  • Is unable to hold his or her head steady for the duration of study measurements.

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

30 participants in 1 patient group

normal healthy group
Experimental group
Description:
Spatial light modulator
Treatment:
Device: Spatial light modulator

Trial contacts and locations

0

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Central trial contact

Jiakai Lyu, MS; Geunyoung Yoon, PhD

Data sourced from clinicaltrials.gov

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