Vitamin A and Azithromycin for Acne Vulgaris

Manchanda Medical Clinic

Status and phase: Unknown; Early Phase 1

Conditions: Acne Vulgaris

Treatments: Drug: Vitamin A; Drug: Azithromycin

Study type: Interventional

Funder types: Other

Identifiers

NCT03090048

Tawar -1

Details and patient eligibility

About

Patients seen with acne lesions not having responded to existing treatments will be offered a placebo or a topical preparation consisting of Vitamin A USP with or without Azithromycin for a duration of 4-6 months USP for the objective of resolving the lesions without systemic side effects and via weekly follow-ups.

Full description

The concentrations of the active ingredients is based on the enclosed articles and the formulations have been modified with an objective of minimizing the side effects.

Enrollment: 30 estimated patients

Sex: All

Ages: 12 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with active lesions

Exclusion criteria

• Patients on a treatment
• Asymptomatic patients

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 3 patient groups

Vitamin A

Experimental group

Description:

retinyl palmitate USP

Treatment:

Drug: Vitamin A

Azithromycin with Vitamin A

Experimental group

Description:

USP grade ingredients

Treatment:

Drug: Azithromycin

Drug: Vitamin A

Azithromycin

Active Comparator group

Description:

azithromycin monohydrate

Treatment:

Drug: Azithromycin