Vitamin A in Cord Blood and Preterm Outcomes

Jilin University

Status: Not yet enrolling

Conditions: Extremely Premature Infant

Study type: Observational

Funder types: Other

Identifiers

NCT07296393

25K281-001

Details and patient eligibility

About

This single-center prospective cohort study aims to describe the distribution of umbilical-cord blood vitamin A concentrations in extremely preterm infants (<32 weeks' gestation) and to evaluate whether low cord blood vitamin A is associated with increased risk of neonatal morbidities such as bronchopulmonary dysplasia (BPD), necrotising enterocolitis (NEC), severe intraventricular haemorrhage (IVH), retinopathy of prematurity (ROP), periventricular leukomalacia (PVL), high-grade patent ductus arteriosus (hsPDA), respiratory distress syndrome (RDS), sepsis and death before discharge.

Enrollment: 155 estimated patients

Sex: All

Ages: Under 28 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

Gestational age <32 weeks Birth at First Hospital of Jilin University Umbilical cord blood sample obtained within 24 h Parental written informed consent

Exclusion criteria

Major congenital malformation or chromosomal abnormality Refusal of consent

Trial design

155 participants in 1 patient group

Extremely Preterm Infants