Vitamin A, Its Receptors and Asthma

Kansas Board of Regents

Status: Withdrawn

Conditions: Asthma

Study type: Observational

Funder types: Other

Identifiers

NCT00628329

11213

Details and patient eligibility

About

We wish to understand the association of Vitamin A serum levels and Vitamin A receptor number and responsiveness in asthmatics. We believe that Vitamin A receptors may be less prevalent in asthmatics and their responsiveness decreased.

Full description

We wish to define the association of asthma, vitamin A serum levels and vitamin A receptor number and responsiveness on circulating mononuclear cells. Asthma is a complex, heterogenous and often debilitating and potentially deadly disease. The causes for asthma are many, with susceptibility and resistance to treatment is poorly understood. Ultimately, looking at this disease from another angle such as the role of Vitamin A and/or receptors can help us learn more about the pathophysiology and treatment of asthma.

Sex: All

Ages: 18 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with previously diagnosed asthma on inhaled corticosteroids, systemic steroids and/or long acting beta agonist (for a period of 6 mo to 5 years)
• Age 18-64
• Male or female

Exclusion criteria

• Children under age 18
• Adults 65 or older
• Patients with COPD

Trial design

0 participants in 2 patient groups

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