Vitamin C & Exercise Induced Bronchoconstriction (EIB)
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Details and patient eligibility
About
The purpose of this research is to assess the association between diet and pulmonary function during standardized EIB testing. Determine the effect of Vitamin C supplementation on airway inflammatory markers and bronchoconstriction after a standardized EIB test compared to usual diet and placebo control.
Full description
This study will use a double-blind, randomized, cross-over design with subjects serving as their own controls. This study will be conducted over a consecutive five-week period.
All subjects will be asked to discontinue taking their short- and long-acting beta-agonist medication 12 and 24 hours respectively prior to data collection. Also, all subjects will be asked to refrain from caffeine, physical activity, and NSAID use 24 hours prior to testing. In addition all subjects will be asked to abstain from taking any vitamin supplement during the course of the study.
Sex
Ages
Volunteers
Inclusion criteria
- Student or student-athlete who has tested positive for EIB
- Able to communicate in English
Exclusion criteria
- Forced expiratory volume in 1 second (FEV1) < 70% of predicted, cardiac history,
- Current respiratory infection
- > 10 pack year history of smoking
- Pregnancy.
Trial design
Primary purpose
Allocation
Interventional model
Masking
0 participants in 2 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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