Vitamin C Mesotherapy Versus Diode Laser for the Management of Physiologic Gingival Pigmentation

Hams Hamed Abdelrahman

Status: Completed

Conditions: Gingival Pigmentation

Treatments: Other: Vitamin C mesotherapy; Radiation: Diode laser

Study type: Interventional

Funder types: Other

Identifiers

NCT05608057

Laser_VitC2022

Details and patient eligibility

About

Physiologic pigmentation affects the gingival esthetics. Laser ablation has been recently used as the most effective and reliable technique for gingival depigmentation. However, the high cost of laser technology limits its use in dental practice. Vitamin C/Ascorbic acid mesotherapy has been proposed as a minimally invasive, safe, cost-effective new modality of treatment.

Enrollment: 26 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults between 18 and 45 years old with physiologic melanin pigmentation in the anterior esthetic portion of the maxillary or mandibular gingiva.
• Systemically free

Exclusion criteria

• Smokers.
• Drugs intake, which associates with gingival melanin pigmentation.
• Pregnant and lactating women.
• Patients with known hypersensitivity to ascorbic acid.
• Patients with bad oral hygiene.
• Pigmentation of the gingiva due to heavy metal ingestion

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

26 participants in 2 patient groups

Vitamin C mesotherapy

Experimental group

Treatment:

Other: Vitamin C mesotherapy

Diode laser

Active Comparator group

Treatment:

Radiation: Diode laser