Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus (Vit C)

Al-Neelain University

Status and phase: Unknown; Phase 1

Conditions: Type 2 Diabetes Mellitus

Treatments: Dietary Supplement: Vitamin C; Drug: glyburide

Study type: Interventional

Funder types: Other

Identifiers

NCT01319734

22

Details and patient eligibility

About

Null hypothesis:

No significant effect of vitamin C 500 mg Supplementation on the severity of micro-vascular complications of type 2 Diabetes Mellitus (DM).

Alternative hypothesis:

There is a significant effect of vitamin C 500mg supplementation on the severity of the micro-vascular complications of type 2DM.

Enrollment: 50 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical diagnosis of type 2DM
• patients in good health
• receiving oral hypoglycemic drugs

Exclusion criteria

• Insulin dependent diabetes
• receiving vitamin complex
• smoking
• renal disease
• liver disease

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Vitamin C supplementation plus oral hypoglycemic agents arm

Experimental group

Description:

This group will receive vitamin C supplementation 500mg daily for one month and then assessment will done for the patients.

Treatment:

Dietary Supplement: Vitamin C

Type 2DM patients receiving oral hypoglycemic agents alone

Active Comparator group

Description:

this group is the control group who receive oral hypoglycemic agents alone

Treatment:

Drug: glyburide