Vitamin D and T-Regulatory Cells in Coronary Artery Disease

Creighton University

Status: Terminated

Conditions: Coronary Artery Disease; Cardiovascular Disease

Treatments: Other: No medication; Dietary Supplement: Vitamin D

Study type: Interventional

Funder types: Other

Identifiers

NCT01183962

09-15602

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of Vitamin D supplementation on cardiovascular disease and certain cells (T-regulatory cells) in the body that play a role in plaque formation in arteries. This study will determine the levels of Vitamin D and T-regulatory cells in subjects with coronary artery disease and if Vitamin D supplementation will affect future events such as heart attach and stroke.

Enrollment: 50 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• between the ages of 30 and 80 years
• have a history of medically treated coronary artery disease

Exclusion criteria

• history of smoking in the past 2 years
• history of diabetes mellitus

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Vitamin D

Other group

Description:

Subject receives daily dose of Vitamin D

Treatment:

Dietary Supplement: Vitamin D

No medicine

Other group

Description:

Subject does not receive medication

Treatment:

Other: No medication