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Vitamin D and Type 2 Diabetes - a Cross Sectional Study

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University of Aarhus

Status

Completed

Conditions

Type 2 Diabetes Mellitus
Hypovitaminosis D

Study type

Observational

Funder types

Other

Identifiers

NCT00695474
M-20080061

Details and patient eligibility

About

The purpose of the study is to describe vitamin D status among patients with type 2 diabetes and to determine the association between serum 25-hydroxyvitamin D and glycemic control, markers of inflammation and blood pressure

Full description

It has been estimated that 1 billion people worldwide have vitamin D deficiency or insufficiency. It is well known that vitamin D deficiency causes osteoporosis, increases the risk of fracture and causes muscle weakness. But there is now evidence that calcium malnutrition and hypovitaminosis D are predisposing conditions for various common chronic diseases such as malignancies (particularly colon, breast and prostate) chronic inflammatory and autoimmune disease (inflammatory bowel disease, multiple sclerosis) as well as metabolic disorders (metabolic syndrome, hypertension).

It has also been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus.

The purpose of this study is to determine vitamin D status among type 2 diabetics in our outpatient clinic and examine the relationship between vitamin D status , calcium and phosphorous metabolism, inflammatory markers, glycemic control, blood pressure and lipid profile.

Moreover the patients are asked to answer a questionnaire regarding lifestyle, exercise, sun exposure and food intake.

Enrollment

150 patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Type 2 diabetes mellitus
  • Patients of Danish extraction
  • Written consent

Exclusion criteria

  • Renal failure (Urea > 12 mmol/l)
  • Age < 18 years
  • malabsorption

Trial design

150 participants in 1 patient group

A
Description:
The cohort consists of type 2 diabetics from the outpatient clinic at Silkeborg Hospital.

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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