Vitamin D Deficiency As a Risk Factor for the Development and Malignant Transformation of Oral Lichen Planus

Fayoum University

Status

Completed

Conditions

Oral Lichen Planus

Vitamin D Deficiency

Treatments

Device: ELISA

Study type

Observational

Funder types

Other

Identifiers

NCT06033105

2191982

Details and patient eligibility

About

To examine how a lack of vitamin D may increase the risk of developing oral lichen planus and its malignant progression while accounting for sex, food habits, sunlight, socioeconomic level, and psychological variables.

Enrollment

70 patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

(Group A) patients presenting with a clinical picture and histological findings that confirm the diagnosis of OLP
(Group B) age, sex, and dietary habits matched healthy controls.

Exclusion criteria

(1) subjects who have been receiving any kind of VD supplements, multivitamins, or any drug that may affect VD measurements
(2) patients with suspected restoration-related or smokeless tobacco-related lesions.
(3) patients with any systemic medical condition or pregnant females.
(4) patients with VD toxicity (VD≥100 ng/ml).