Vitamin D for Improving Metabolic Control and Depressive Symptoms

Loyola University

Status

Completed

Conditions

Depressive Symptoms

Diabetes

Treatments

Dietary Supplement: Vitamin D supplementation

Study type

Interventional

Funder types

Other

Identifiers

NCT01185574

201255

Details and patient eligibility

About

This study will examine whether weekly vitamin D supplementation in women with significant depressive symptoms and diabetes will exhibit improved mood and metabolic control. If supplementation with Vitamin D is beneficial, it will be a simple and cost-effective method for treatment. Women will be targeted since they have greater depression and worse metabolic control than men with diabetes.

Enrollment

50 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Women aged 18 and older
medically stable type 2 diabetes with HBA1c <9%.
significantly elevated depressive symptoms as measured by a score greater than or equal to 14 using the Center for Epidemiologic Studies Depression Tool (CES-D.

Exclusion criteria

vitamin D levels of 32 ng/dl or greater
malabsorption problems (e.g., crohn's disease, celiac sprue)
hypercalcemia-level greater than 10.5 mg/dl
Severe complications of diabetes (amputation, blindness, or renal problems) 5) Women with low thyroid function

active suicidal ideation, a history of bipolar depression, psychotic disorders, and current alcohol or substance disorders. Active treatment for depression (e.g., antidepressant therapy) will not be exclusion criteria 7) Any serious chronic illness that may impact on their health-related quality of life and treatment effect 8) Women who are pregnant 9) Women who have had bariatric surgery.