Vitamin D, HbA1c and Vitamin B12 Levels in Patients

Hacettepe University

Status: Completed

Conditions: Serum HbA1c and Vitamin D, Vitamin B12 Values in Periodontal Diseases

Treatments: Diagnostic Test: HbA1c, Vitamin D, Vitamin B12

Study type: Observational

Funder types: Other

Identifiers

NCT05745779

2022/81

Details and patient eligibility

About

Abstract Aim: to compare the serum vitamin D, HbA1c and vitamin B12 levels in patients with gingivitis and four different periodontitis stages diagnosed according to the 2017 Periodontal Disease Classification.

Materials and methods: A total of 606 (378 Female, 228 Male) patients were included in the study. The periodontal status of the patients was diagnosed with gingivitis, stage 1,2,3 and 4 periodontitis groups were formed. HbA1c, vitamin D and vitamin B12 values of the patients were compared and analyzed.

Result:

Conclusion:

Full description

bstract Aim: to compare the serum vitamin D, HbA1c and vitamin B12 levels in patients with gingivitis and four different periodontitis stages diagnosed according to the 2017 Periodontal Disease Classification as determined by the American Academy of Periodontology and the European Federation of Periodontology (AAP-EFP) Materials and methods: A total of 606 (378 Female, 228 Male) patients were included in the study. The periodontal status of the patients was diagnosed with gingivitis, stage 1,2,3 and 4 periodontitis groups were formed. HbA1c, vitamin D and vitamin B12 values of the patients were compared and analyzed.

Enrollment: 606 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with gingivitis or periodontitis with complete periodontal diagnostic data (Gingival Index(Löe, 1967), Plaque Index(Löe, 1967), Periodontal pocket depths(PD), Clinical Attachment loss (CAL), Radiological data- Interdental Bone loss (IBL) data
• Non-smoker
• Vit D, HbA1c and B12 vit in blood on the date of application to the clinic and/or in the last 3 months. Patients with data on values were included in the study.

Exclusion criteria

• Patients with missing data and not allowing data use
• Smoker
• The data of pregnant and lactating patients were not included in the study.

Trial design

606 participants in 5 patient groups

Gingivitis

Description:

0% interdental bone loss

Treatment:

Diagnostic Test: HbA1c, Vitamin D, Vitamin B12

Stage 1 periodontitis

Description:

0-15% interdental bone loss

Treatment:

Diagnostic Test: HbA1c, Vitamin D, Vitamin B12

Stage 2 Periodontitis

Description:

15-33% interdental bone loss

Treatment:

Diagnostic Test: HbA1c, Vitamin D, Vitamin B12

Stage 3 Periodontitis

Description:

\>33% interdental bone loss with potential for additional tooth loss

Treatment:

Diagnostic Test: HbA1c, Vitamin D, Vitamin B12

Stage 4 Periodontitis

Description:

\>%33 interdental bone loss with potantial for loss of dentition

Treatment:

Diagnostic Test: HbA1c, Vitamin D, Vitamin B12