Vitamin D in Vulnerable Adults (VIVA-VA)

VA Office of Research and Development

Status and phase: Completed; Phase 3

Conditions: Vitamin d Deficiency; Frail Elderly

Treatments: Dietary Supplement: placebo; Dietary Supplement: vitamin D

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT01170273

F7574-R

Details and patient eligibility

About

Vitamin D insufficiency is a problem of growing concern, given its prevalence in older persons and the association of low vitamin D with multiple major health problems, including mobility and balance deterioration and falls, cardiovascular disease, diabetes, and certain cancers. Sedentary persons are particularly vulnerable for these health problems and generally not adherent to prescribed physical activity. This study will investigate if treatment with vitamin D will benefit physical performance in male veterans age 65 to 95.

Enrollment: 130 patients

Sex: Male

Ages: 65 to 95 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• male veterans
• 65 to 95 years of age
• independent
• sedentary
• vitamin D insufficiency

Exclusion criteria

• hypercalcemia
• renal failure
• living in a nursing home

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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130 participants in 2 patient groups, including a placebo group

Placebo Arm

Placebo Comparator group

Description:

placebo capsule

Treatment:

Dietary Supplement: placebo

Cholecalciferol 4000 IU

Experimental group

Description:

cholecalciferol 4000 IU daily

Treatment:

Dietary Supplement: vitamin D