Vitamin D Levels in Frail Elderly Patients With a Hip Fracture

University of Aarhus

Status: Completed

Conditions: Vitamin D Deficiency; Hip Fracture

Study type: Observational

Funder types: Other

Identifiers

NCT01816711

2007-58-0010 (Other Identifier)

HFVD2012

Details and patient eligibility

About

The purpose of this study is to assess whether all frail elderly admitted with hip fracture has a vitamin D deficiency, and if s-25(OH)D deficiency increases the risk of hip fracture in frail elderly.

Frail elderly are defined as being 65 years of age or older, and living in nursing homes or senior housings.

The investigators' hypotheses state that:

1. Frail elderly with hip fractures will have a suboptimal level of vitamin D.
2. Frail elderly with hip fractures are more likely to have a suboptimal level of vitamin D than frail elderly without any hip fractures during the last ten years.

Full description

The study examined frail elderly patients, defined as 65 of age or older and living nursing homes or senior housings.

Cases where taken from a Randomised Controlled Trial (NCT01102010), where the included where frail elderly admitted with a hip fractures to the Orthopaedic Surgery Ward at Aarhus University Hospital.

Controls were frail elderly, without a hip fracture in the previous ten years, admitted to the Geriatric Ward at Aarhus University Hospital.

The investigators will look at all eligible patients' files and record their serum-25(OH)D levels upon admission.

According to sample size calculations 92 patients are needed in the case group, and 138 patients in the control group.

The inclusion period will be from the 18th of January 2010 to the 1st of October 2012 for both groups.

Enrollment: 447 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria, Cases:

• Aged 65 or older
• Living in nursing home or senior housing
• Admitted with hip fracture to the Orthopaedic Ward, Aarhus University Hospital

Exclusion Criteria, Cases:

• No serum-25(OH)D measurement upon admission

Inclusion Criteria, Controls:

• Aged 65 or older
• Living in nursing home or senior housing
• Admitted to the Geriatric Ward, Aarhus University Hospital

Exclusion Criteria, Controls:

• No serum-25(OH)D measurement upon admission
• Hip fracture in the previous ten years

Trial design

447 participants in 2 patient groups

Hip fracture, Frail elderly, Non-supplemented

Description:

Frail elderly with a hip fracture who did not received vitamin D supplementation

Hip fracture, Frail elderly, Supplemented

Description:

Frail elderly with a hip fracture who received vitamin D supplementation