Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France (EVADDREP)

Civil Hospices of Lyon

Status: Completed

Conditions: Vitamin D Deficiency; Sickle Cell Disease

Treatments: Biological: 25-OH Vitamin D measure

Study type: Observational

Funder types: Other

Identifiers

NCT04694976

69HCL20_0885

ID-RCB (Other Identifier)

Details and patient eligibility

About

Vitamin D deficiency may be under-diagnosed in sickle cell disease French children. Therefore, the investigator need an epidemiologic study about the prevalence of vitamin D deficiency in this specific population. There are not specific guidelines neither testing nor treatment. The investigator propose to test vitamin D status in all children with sickle cell disease who are consulting their referring haematologist doctor or in the emergency ward.

Enrollment: 130 patients

Sex: All

Ages: Under 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children: under 18 years old
• Sickle cell any genetic type homozygous or composite heterozygous
• To receive an assessment independently of the study, during a presentation to the emergency ward and/or a follow-up consultation by the hematologist
• no parental opposition signed by at least one parent/legal representative and no child opposition
• social security beneficiary

Exclusion criteria

• History of hematologic grafting

Trial design

130 participants in 1 patient group

Sickle cell disease children from Lyon, France

Description:

Sickle cell disease children, followed in IHOPe (Institut d'Hématologie et d'Oncologie Pédiatrique) center, consulting their referring haematologist doctor or in emergency ward, with prescribed blood sample.

Treatment:

Biological: 25-OH Vitamin D measure