Vitamin D Supplementation and WBV in Inflammatory Markers, Strength and Body Composition in Old Patients With COPD

Maíra F Pessoa

Status: Unknown

Conditions: Aging; COPD

Treatments: Dietary Supplement: Vitamin D; Other: whole body vibration (WBV)

Study type: Interventional

Funder types: Other

Identifiers

NCT03684330

croninflam

Details and patient eligibility

About

Verify the influence off vitamin D supplementation and a whole body vibration (WBV) protocol during 03 months in older patients chronic obstructive pulmonary disease

Enrollment: 59 patients

Sex: All

Ages: 60 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Older patients with COPD
• Both genders
• Sedentary according to International Physical Activity Questionnaire (IPAQ) short form
• BMI in between 22.9 and 28 kg/m2.
• Older patients with COPD should have a clinical-functional diagnosis of the disease according to GOLD (GOLD, 2018), have been ex-smokers and have not used corticosteroids or have used this drug in a stable way for at least one year (without dosage or medication modifications).
• Older volunteers should be self-referenced healthy or, if they had systemic arterial hypertension or diabetes mellitus, these comorbidities should be controlled by diet or regular medication use.

Exclusion criteria

• Older patients with COPD who had episodes of exacerbation in the last three months, those with pulmonary rehabilitation programs in the last year, those who used home oxygen therapy, and patients with COPD associated comorbidities were excluded.
• Volunteers of both groups who were taking vitamin D were excluded, as well as the current smokers, although occasional, volunteers with a history of labyrinthitis or thromboembolism, who had undergone surgical procedures of any size in the last year, such as plaques, pins or cardiac pacemakers, those with unconsolidated fractures that used medications that affected bone metabolism or lean mass, or those who had difficulties adapting to the assessment or the training protocol.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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59 participants in 2 patient groups, including a placebo group

Vitamin D supplementation

Active Comparator group

Treatment:

Dietary Supplement: Vitamin D

Other: whole body vibration (WBV)

Vitamin D placebo

Placebo Comparator group

Treatment:

Other: whole body vibration (WBV)