Vitamin D Supplementation for the Prevention of Acute Respiratory Tract Infections

Tampere University

Status: Completed

Conditions: Respiratory Tract Infections

Treatments: Dietary Supplement: vitamin D; Dietary Supplement: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT00973583

UTampere-RO5125

Details and patient eligibility

About

The investigators earlier clinical study in 754 young Finnish men demonstrated a significant negative association of serum 25-OHD concentration with acute respiratory tract infections. The present study aimed to determine whether vitamin D supplementation may decrease the incidence of acute respiratory tract infections.

Full description

Subjects comprised 164 male conscripts at a military base in Finland. Half of the participants were randomly allocated to receive 400 IU vitamin D daily and half received placebo from October through March. Serum vitamin D and plasma parathyroid hormone concentrations were determined. Subjects were followed for 6 months and the primary outcome was the number of days absent from duty due to ARTI.

Enrollment: 164 patients

Sex: Male

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Exclusion Criteria:

• Use vitamin D

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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164 participants in 2 patient groups, including a placebo group

vitamin D

Active Comparator group

Treatment:

Dietary Supplement: vitamin D

placebo

Placebo Comparator group

Treatment:

Dietary Supplement: placebo