Vitamin D3 Levels in COVID-19 Outpatients From Western Mexico

University of Guadalajara

Status: Completed

Conditions: Covid19

Treatments: Dietary Supplement: Vitamin D3

Study type: Interventional

Funder types: Other

Identifiers

NCT04793243

CI-07620

Details and patient eligibility

About

The immunomodulatory effects of vitamin D are known to be beneficial in viral infections, it is also known that its deficiency is associated with a worse prognosis of COVID-19. This study aimed to determine the baseline vitamin D serum concentrations in asymptomatic or mildly symptomatic COVID-19 outpatients, as well as to evaluate the effects of supplementation with 10,00 IU/daily of vitamin D3 and its relationship with biochemical parameters and clinical features.

Enrollment: 42 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Intervention group: Patients with positive PCR for COVID-19 of both sexes supplemented with vitamin D
• Control group: Patients with positive PCR for COVID-19 of both sexes
• Both groups: Mexican individuals, after signing the informed consent letter and over 18 years of age.

Exclusion criteria

• Diseases that compromise the absorption of Vitamin D; Crohn's disease, cystic fibrosis, and celiac disease.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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42 participants in 2 patient groups

Intervention group

Experimental group

Description:

Formed by 22 patients that received oral supplementation of 10,000 IU daily for fourteen days of vitamin D3

Treatment:

Dietary Supplement: Vitamin D3

Control group

No Intervention group

Description:

Formed by 20 patients that did not receive supplementation