viTAmin K2 and rEcOVery From ExeRcise (TAKEOVER)

University of Glasgow

Status

Completed

Conditions

Inflammation

Vitamin K

Strength

Oxidative Stress

Recovery

Exercise

Treatments

Dietary Supplement: Vitamin K2

Dietary Supplement: Micro-crystalline cellulose

Study type

Interventional

Funder types

Other

Identifiers

NCT04676958

200190189

Details and patient eligibility

About

The aim of the current study, therefore, is to investigate the effects of vitamin K2 supplementation on the physiological responses to an acute bout of resistance exercise.

Enrollment

80 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Participant is able and willing to sign the Informed Consent From
No plans to change lifestyle (activity and nutrition) during the study period
Older group (n=40): 65 years of age or older.
Younger group (n=40): Aged 18-40 years

Exclusion criteria

Not currently, or in the last year, participating in more than 1h per week of vigorous aerobic physical activity or any resistance exercise
BMI > 30 kg/m2
diabetes
severe cardiovascular disease
seizure disorders
liver disease
uncontrolled hypertension (>150/90mmHg at baseline measurement)
cancer or cancer that has been in remission <5 years
ambulatory impairments which would limit ability to perform assessments of muscle function
dementia
currently taking Vitamin K2 supplements
currently taking Vitamin K antagonists/anticoagulants (e.g. warfarin)
current smoking
history of drug abuse
taking medication known to affect muscle (e.g. steroids).