Vitamin Metabolism in Kidney Disease

Aalborg University Hospital

Status: Unknown

Conditions: Kidney Failure

Study type: Observational

Funder types: Other

Identifiers

NCT00257439

VN 2005/44

Details and patient eligibility

About

The purpose of this study is to evaluate the urinary excretion and renal metabolism of vitamins, in particular vitamin B12 and folate, in relation to various renal conditions involving loss of renal function and/or proteinuria.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Admission to the Department of Nephrology, Aalborg Hospital
• Elevated serum creatinine
• Proteinuria
• Informed and written consent

Control subjects:

• Normal serum creatinine and creatinine clearance
• No proteinuria

Exclusion criteria

• Vitamin supplementation (exceeding predefined values)
• Renal replacement therapy (dialysis)

Trial design

100 participants in 2 patient groups

CKD

Description:

Elevated se-creatinine + proteinuria

Healthy controls

Description:

Healthy controls, normal se-creatinine, no proteinuria